Research groups
Richard Tyser
BHF Immediate Fellow
Recent publications
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A single-cell molecular map of mouse gastrulation and early organogenesis.
Journal article
Pijuan-Sala B. et al, (2019), Nature, 566, 490 - 495
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Defining murine organogenesis at single-cell resolution reveals a role for the leukotriene pathway in regulating blood progenitor formation.
Journal article
Ibarra-Soria X. et al, (2018), Nat Cell Biol, 20, 127 - 134
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Calcium handling precedes cardiac differentiation to initiate the first heartbeat.
Journal article
Tyser RC. et al, (2016), Elife, 5
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Inhibition of NAADP signalling on reperfusion protects the heart by preventing lethal calcium oscillations via two-pore channel 1 and opening of the mitochondrial permeability transition pore.
Journal article
Davidson SM. et al, (2015), Cardiovasc Res, 108, 357 - 366
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Effects of cholesterol depletion on compartmentalized cAMP responses in adult cardiac myocytes.
Journal article
Agarwal SR. et al, (2011), J Mol Cell Cardiol, 50, 500 - 509