Noelia Martínez Sánchez

In the group of Dr. Ana Domingos, I study the neuro mechanisms underlying obesity which could suitable for an anti-obesity therapy.  My project here will broaden my understanding on molecular pathways implicated in energy balance and the sympathetic regulation of fat. I will employ a multidisciplinary approach, combining bioinformatics analysis with genetics and molecular biology studies to identify neuro-excitatory drug targets in sympathetic inputs to adipose tissue. This could lead to the development of drugs that would not have side serious effects. 

I obtained my PhD in Endocrinology from the University of Santiago de Compostela (Spain) in 2016, where I worked in the laboratory of the Prof. Miguel López and Prof. Carlos Dieguez focused in understand how the thyroid hormones regulate the energy balance, and particularly how they exert their action in peripheral metabolic organs through the influence in specific areas of the central nervous system. After that, I had the opportunity to do my first postdoc in Lisbon, with the Dr. Ana Domingos, gaining knowledge in the peripheral connections between the autonomic nervous system and the fat depots. There, I also participated in others strong research lines implicating the immune system, increasing thereby my knowledge in other metabolic systems implicated in the obesity.