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Matthieu Trigano

Postdoctoral Neuronal Cell Biologist

Research Summary

In patients with Parkinson’s disease, the autophagy lysosomal pathway is defective and ultimately result in neuronal degeneration hence the importance to identify potential target drugs. Autophagy is particularly important in postmitotic cells (such as neurons) in order to mediate proteins turnover as well as clear misfolded or aggregate proteins. In collaboration with AstraZeneca, my research focuses on screening for potential drugs that would enhance the autophagic flux in Parkinson’s disease.


I obtained a Bachelor in biotechnology from SUPBiotech, an engineering school in Paris. At Pierre et Marie Curie university, I obtained a Masters in Neuroscience. I then moved to the United Kingdom where I completed a PhD in Neuroscience at Cardiff University.