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Luke Barnes
FHS Student
Xin Su Ning (XSN) is a herbal medicine licensed in China for the treatment of arrhythmias. In order to further our understanding of XSN's mechanism of action, we are investigating the contribution of individual compounds to its anti-arrhythmic effects. My experiments have focussed on characterising the effect of Epiberberine, a compound from the Coptis plant, on expressed human cardiac sodium channels (NaV1.5).