- Hens Group Research Group
Korneel Hens graduated as a biochemist at the University of Leuven before starting a PhD at the same university studying substrate specificity of insect angiotensin converting enzymes. As a post-doc in the lab of Patrick Callaerts he used micro-array and cell culture experiments to identify transcriptional targets of Drosophila paired box transcription factors. Korneel then joined the lab of Bart Deplancke at the EPFL in Switzerland, developing novel technologies for protein-DNA interaction mapping.
Korneel arrived in Oxford in 2012, taking up a group leader position at the Centre for Neural Circuits and Behaviour. His lab continues developing next generation technologies for gene regulatory network mapping, but also focusses on applying these techniques to study the transcriptional regulation of behaviour.
Automated protein-DNA interaction screening of Drosophila regulatory elements.
Hens K. et al, (2011), Nat Methods, 8, 1065 - 1070
Primer-initiated sequence synthesis to detect and assemble structural variants.
Massouras A. et al, (2010), Nat Methods, 7, 485 - 486
Conserved role for the Drosophila Pax6 homolog Eyeless in differentiation and function of insulin-producing neurons.
Clements J. et al, (2008), Proc Natl Acad Sci U S A, 105, 16183 - 16188
Potential Direct Regulators of the Drosophila yellow Gene Identified by Yeast One-Hybrid and RNAi Screens.
Kalay G. et al, (2016), G3 (Bethesda), 6, 3419 - 3430
Mood stabilizing drugs regulate transcription of immune, neuronal and metabolic pathway genes in Drosophila.
Herteleer L. et al, (2016), Psychopharmacology (Berl), 233, 1751 - 1762
A large-scale, in vivo transcription factor screen defines bivalent chromatin as a key property of regulatory factors mediating Drosophila wing development.
Schertel C. et al, (2015), Genome Res, 25, 514 - 523
Conservation of transcription factor binding specificities across 600 million years of bilateria evolution.
Nitta KR. et al, (2015), Elife, 4
Neprilysins: an evolutionarily conserved family of metalloproteases that play important roles in reproduction in Drosophila.
Sitnik JL. et al, (2014), Genetics, 196, 781 - 797