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Insulin Secretion

Jeroen De Baaij


Rubicon Fellow


Jeroen de Baaij  studied Medical Biology at the Radboud University Nijmegen from 2005-2008. From 2008-2010 he enrolled in the Master of Integrative Biology with specialization Physiology and pathophysiology at the Université Pierre et Marie Curie in Paris, France. Subsequently, he started as PhD Student at the department of Physiology, Radboud university medical center, Nijmegen, in 2010. Under the supervision of Prof. Dr. Joost G.J. Hoenderop and Prof. Dr. René J.M. Bindels, he focused on new genes involved in the regulation of magnesium transport in the kidney. After obtaining his PhD degree, Jeroen was awarded a Rubicon grant which allowed him to join the department as post doctoral researcher. Jeroen’s current work focusses on the role of magnesium in the development of type 2 diabetes mellitus in the group of Prof. dr. Frances Ashcroft.


Hypomagnesaemia (serum magnesium (Mg2+) <0.7 mmol/L) has been strongly associated with type 2 Diabetes Mellitus (T2DM). Patients with reduced serum Mg2+ concentrations show a more rapid disease progression. Moreover, dietary Mg2+ supplementation for patients with T2DM improves glucose metabolism and insulin sensitivity. However, the molecular mechanism by which Mg2+ improves T2DM has not been elucidated yet.

As postdoctoral researcher at the Department of Physiology, Anatomy and Genetics of the University of Oxford, I aim to understand the molecular mechanisms by which Mg2+ slows down the progression of T2DM. Our studies propose that hypomagnesaemia contributes to the pathogenesis of T2DM.

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Recent Publications

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