Postdoctoral Research Scientist
Patients with Barrett's oesophagus are at risk of developing oesophageal adenocarcinoma and currently undergo regular tissue biopsy by endoscopy to monitor their condition. Extracellular vesicles from blood or serum provide a potential novel mechanism to detect early progression to cancer. Mass spectrometry analysis of extracellular vesicles isolated from cell lines and patient samples is being used to determine protein signatures associated with different disease stages. The aim is to identify novel biomarkers that would enable early detection of cancer in these patients by a non-invasive liquid biopsy test.