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Research groups

James Cantley

PhD, MSc, DIC, BSc (Hons)

RD Lawrence Fellow

I am an RD Lawrence Fellow, funded by Diabetes UK, a Research Fellow at Wolfson College and a Lecturer in Medicine at Christ Church. My current research interests revolve around the beta cell: how insulin secretory capacity is matched to demand during health and obesity, and how this fails during type 2 diabetes. 

I collaborate with several other research groups including Prof. Heidi De Wet (DPAG), Prof. Helen Christian (DPAG), Dr. Reshma Ramracheya and Prof. Patrik Rorsman (OCDEM, Oxford).

I undertook my doctoral studies in the lab of Prof. Dominic Withers at University College London, where I investigated the molecular control of beta cell function by oxygen sensing and insulin signalling pathways. I received my PhD in 2007 and went on to a postdoctoral position at the Garvan Institute of Medical Research, Sydney, where I worked in the lab of Prof. Trevor Biden, and developed my interests in lipid signalling processes in the beta cell. Whilst in Australia I held two consecutive postdoctoral fellowships enabling me to develop my own research direction. I returned to the UK in 2013 to take up my current position as group leader within the Department of Physiology, Anatomy and Genetics at the University of Oxford.

Key publications

Recent publications

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