DPhil, MPhys (Hons Oxon), AFHEA, MInstP, MIPEM
Novo Nordisk Postdoctoral Fellow
- Junior Research Fellow in Medical Physics, Wadham College; Stipendiary Lecturer in Physics, St Hugh's College
I am an interdisciplinary medical physicist with an interest in metabolic imaging, MRI, and the application of quantitative tools to study relevant problems in biology.
My work focuses on the role metabolism plays in cardiac pathology, and I am in the enviable position of being able to follow biochemical fluxes through metabolic pathways in real-time, in living systems, ranging from isolated enzymes through to patients in the John Radcliffe Hospital.
-insensitive, dual-band quasi-adiabatic saturation transfer with optimal control for complete quantification of myocardial ATP flux.
Miller JJ. et al, (2021), Magn Reson Med, 85, 2978 - 2991
Proof-of-Principle Demonstration of Direct Metabolic Imaging Following Myocardial Infarction Using Hyperpolarized 13C CMR.
Apps A. et al, (2021), JACC Cardiovasc Imaging
A 3D hybrid-shot spiral sequence for hyperpolarized
Tyler A. et al, (2021), Magn Reson Med, 85, 790 - 801
Early detection of doxorubicin-induced cardiotoxicity in rats by its cardiac metabolic signature assessed with hyperpolarized MRI.
Timm KN. et al, (2020), Commun Biol, 3
Nicotinic acid receptor agonists impair myocardial contractility by energy starvation.
Watson WD. et al, (2020), FASEB J, 34, 14878 - 14891