- Wade-Martins Group Research Group
Irene del Molino del Barrio
Postdoctoral Research Scientist
I am currently a postdoctoral researcher in Drug Discovery in Friedreich's Ataxia at Professor Wade-Martins lab in Oxford University. The project stemmed from a collaborative drug discovery effort between Pfizer and the FRDA UK consortium to focus on the identification and validation of novel targets and molecules for the treatment of Friedreich's Ataxia.
Before this, I did my PhD at Newcastle University where I was sponsored by the Women's Cancer Detection Charity in the Queen Elizabeth hospital (Gateshead, UK). The main aim of my doctorate project was to study the role of the chemokine receptors CXCR4 and CXCR7 when forming heterodimers or homodimers, as well as investigating the functional consequences of their expression in tumour progression and metastasis. Previously, I also carried out a Masters in Translational Medicine and Therapeutics and did my undegraduate in Biotechnology from the Autonomous University of Barcelona (UAB). My interests lie in flow cytometry and drug discovery, and I am keen to apply my research so we can bridge the gap between bench and bedside.
The Role of Chemokine and Glycosaminoglycan Interaction in Chemokine-Mediated Migration In Vitro and In Vivo.
del Molino del Barrio I. et al, (2016), 570, 309 - 333
CXCR4 and CXCR7 homodimers and heterodimers play differential roles in breast cancer
DEL MOLINO DEL BARRIO I. et al, AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA