- Wade-Martins Group Research Group
Stem Cell Facility Research Manager
I have joined the Molecular Neurodegeneration Research Group as the Stem Cell Facility Research Manager. My role will include the management of the stem cell culture facilities (specialising in human patient derived iPSCs) as well as providing expertise in using state-of-the-art equipment which includes the ECHO nanodrop dispenser, the Opera Phenix and the PHERAstar FSX HTS microplate reader. These facilities are funded by the Dementia Platform UK (DPUK) Stem Cell Network and the Oxford Parkinson’s Disease Centre. We welcome new collaborations with other research groups, academic or industrial based, to exploit our platform technologies.
I completed my PhD at Keele University investigating the synergistic effects of synthetic electrospun scaffolds and oxygen tension on the expansion of pluripotent human embryonic stem cells. My postdoctoral research experience (Loughborough University and University of Manchester) has largely been at the interface of biomaterials (electrospun devices and hydrogels), tissue engineering, regenerative medicine, bioreactors, stem cells and tissue-specific primary cells. I also have experience in the development of in vitro 3D tissue engineering models, which aim to closely mimic the in vivo extracellular matrix environment, with examples including: bone, anterior cruciate ligament, oesophageal tissue, neural tissue and aortic valves. In my current role we will be exploring integration of iPSC cultures into 3D biomaterials and evaluating iPSC-derived dopaminergic neuronal behaviour and activity.