- Butt Group Research Group
I grew up in Turin, Italy, where I completed a Bachelor in Biotechnology (Distinction) followed by a Master in Molecular Biotechnology (Distinction). My work, supervised by Prof. Ferdinando Di Cunto, focused on the molecular mechanisms underlying microcephaly using in vitro systems to mimic the depletion of key proteins in brain development.
This project, together with a research experience in Prof. Christopher Walsh lab, Boston, studying an in vivo model of microcephaly, raised my deep interested in neuroscience, which led me to move to Oxford and complete an MSc in Neuroscience. During the MSc I worked on dopamine dynamics with Dr Mark Walton and Dr Elizabeth Tunbridge and on the characterization of circuit development in a mouse model of autism with Prof. Simon Butt.
Since October 2015 I have been a DPhil student at Christ Church College, under the supervision of Prof. Simon Butt and Prof. Zoltan Molnar.
Microcephaly Proteins Wdr62 and Aspm Define a Mother Centriole Complex Regulating Centriole Biogenesis, Apical Complex, and Cell Fate.
Jayaraman D. et al, (2016), Neuron, 92, 813 - 828
ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules.
Gai M. et al, (2016), EMBO Rep, 17, 1396 - 1409