Carolina Roque Silva
Research Assistant in Cardiovascular Development and Regeneration
In 2018 I was awarded a BSc in Biochemistry from the University of Lisbon (Portugal) where, during my final year, I undertook an internship at the Biosystems and Integrative Sciences Institute (BioISI). Briefly, I was involved in utilising CRISPR/Cas9-mediated gene editing to knock out ANO1 (which encodes for a chloride channel) in a bronchial epithelial cell line derived from cystic fibrosis patients.
Subsequently, I moved to the UK to study an MSc in Molecular Medicine at the University of Sheffield, graduating in 2019. Here, I conducted a research project which investigated the role of neutrophil-derived microvesicles on lung epithelial cell function in Chronic Obstructive Pulmonary Disease (COPD).
In October 2020, I joined the Vieira group as a Research Assistant to study the role of the noncoding genome in the regulation of epithelial-to-mesenchymal transition (EMT), particularly in the epicardium.