- Szele Group Research Group
Postdoctoral Research Scientist
I am interested in the biological mechanisms underlying neural stem cell maintenance in postnatal and adult mammalian brains, with particular emphasis on epigenetic regulation. The postnatal subventricular zone harbors the largest population of neural stem cells. I try to understand how different epigenetic mechanisms, including histone methylation, long non-coding RNA, DNA element and gene transcription, coordinate to maintain this stem cell pool. I use both in vivo and in vitro models, in combination with genome-wide and transcriptome-wide analysis, with a goal to control stem cell behaviors and improve brain repair.
I obtained Bachelor of Medicine from Zhejiang University in Hangzhou, China (2011) and DPhil from the Department of Physiology, Anatomy and Genetics, University of Oxford (2015). I am currently working as a postdoctoral research scientist (MRC) in the Szele lab.
Traumatic Brain Injury Activation of the Adult Subventricular Zone Neurogenic Niche.
Chang EH. et al, (2016), Front Neurosci, 10
STAT1-induced ASPP2 transcription identifies a link between neuroinflammation, cell polarity, and tumor suppression.
Turnquist C. et al, (2014), Proc Natl Acad Sci U S A, 111, 9834 - 9839