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Research groups


Adam Wells

DPhil Student

Dissecting the molecular basis of exosome production

I study the mechanisms regulating exosome production in multivesicular bodies. In particular I focus on mechanisms which may relate to the role of exosomes in cancer and neurodegenerative disease including examining the role of ESCRT proteins, E-Cadherin and various Rab proteins. My experiments largely utilise the secondary cells of Drosophila flies because of their unique biology which allows us to directly image the events of exosome biogenesis.