Development and evolution of neocortical subplate neurons
Dr Anna Hoerder-Suabedissen, DPAG
Friday, 06 February 2015, 1.30pm to 2pm
Sherrington Large Lecture Theatre, Sherrington Building, off South Parks Road OX1 3PT
If you have a question about this talk, please contact Sarah Noujaim.
Subplate neurons have an essential role in cortical circuit formation. They are amongst the earliest formed neurons of the cerebral cortex, are located at the junction of white and grey matter and necessary for correct thalamocortical axon ingrowth. Recent transcriptomic characterizations provide opportunities for monitoring and modulating selected subpopulations of these cells. Mouse lines expressing reporter genes have demonstrated novel, extra-cortical subplate neurogenesis and shown how subplate cells are integrated under the influence of sensory activity into cortical and extracortical circuits.