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2016

Atherton N, Bridle C, Brown D, Collins H, Dosanjh S, Griffiths F, Hennings S, Khan K, Lall R, Lyle S, McShane R, Mistry D, Nichols V, Petrou S,Sheehan B, Slowther AM, Thorogood M, Withers E, Zeh P, Lamb SE. (2016) Dementia and Physical Activity (DAPA) - an exercise intervention to improve cognition in people with mild to moderate dementia: study protocol for a randomized controlled trial. Trials 17:165. PMID: 27015659 

Bonifacio G, Zamboni G. (2016) Brain imaging in dementia. Postgraduate medical journal. In Press. PMID: 26933232

Dafinca R, Scaber J, Ababneh N, Lalic T, Weir G, Christian H, Vowles J, Douglas AG, Fletcher-Jones A, Browne C, Nakanishi M, Turner MR, Wade-Martins R, Cowley SA, Talbot K. (2016) C9orf72 Hexanucleotide Expansions are Associated with Altered ER Calcium Homeostasis and Stress Granule Formation in iPSC-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Stem Cells. In press. PMID: 27097283. 

Mattsson N, Schott JM, Hardy J, Turner MR, Zetterberg H. (2016) Selective vulnerability in neurodegeneration: insights from clinical variants of Alzheimer's disease. Journal of neurology, neurosurgery and psychiatry. In press. PMID: 26746185. 

Voyle N, Kim M, Proitsi P, Ashton NJ, Baird AL, Bazenet C, Hye A, Westwood S, Chung R, Ward M, Rabinovici GD, Lovestone S, Breen G, Legido-Quigley C, Dobson RJ, Kiddle SJ. (2016) Blood metabolite markers of neocortical amyloid-β burden: discovery and enrichment using candidate proteins. Translational psychiatry. In Press. PMID: 26812040. 

Westwood SLeoni EHye ALynham SKhondoker MRAshton NJKiddle SJBaird ALSainz-Fuertes RLeung RGraf JHehir CT,Baker DCereda CBazenet CWard MThambisetty MLovestone S. (2016) Blood-Based Biomarker Candidates of Cerebral Amyloid Using PiB PET in Non-Demented Elderly. Journal of Alzheimer's Disease. In Press. PMID: 27031486. 

2015

Allan CL, Zsoldos E, Filippini N, Sexton CE, Topiwala A, Valkanova V, Singh-Manoux A, Tabák AG, Shipley MJ, Mackay C, Ebmeier KP, Kivimäki M (2015) Lifetime hypertension as a predictor of brain structure in older adults: cohort study with a 28-year follow-up. Br J Psychiatry. 206(4):308-15. PMID: 25497301

Baird AL, Westwood S, Lovestone S (2015) Blood-Based Proteomic Biomarkers of Alzheimer's Disease Pathology. Frontiers in Neurology, Volume 6: Article 236. PMID: 26635716

Esiri M, Chance S, Joachim C, Warden D, Smallwood A, Sloan C, Christie S, Wilcock G, Smith AD. (2015) Cerebral amyloid angiopathy, subcortical white matter disease and dementia: literature review and study in OPTIMA. Brain Pathol. 25(1):51-62. PMID: 25521177

Harrison JK, Fearon P, Noel-Storr AH, McShane R, Stott DJ, Quinn TJ. (2015) Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the diagnosis of dementia within a secondary care setting. Cochrane Database Syst Rev. 3:CD010772. PMID: 25754745

McCleery J, Morgan S, Bradley KM, Noel-Storr AH, Ansorge O, Hyde C. (2015) Dopamine transporter imaging for the diagnosis of dementia with Lewy bodies. Cochrane Database Syst Rev. 30;1:CD010633. PMID: 25632881

Pendlebury STKlaus SPMather Mde Brito MWharton RM. Routine cognitive screening in older patients admitted to acute medicine: abbreviated mental test score (AMTS) and subjective memory complaint versus Montreal Cognitive Assessment and IQCODE. Age and Ageing. In press. PMID: 26464420.  

Pendlebury STKlaus SPThomson RJMehta ZWharton RMRothwell PMMethodological Factors in Determining Risk of Dementia After Transient Ischemic Attack and Stroke: (III) Applicability of Cognitive Tests. Stroke. In Press. PMID: 26463688  

Pineda-Pardo JA, Bruña R, Woolrich M, Marcos A, Nobre AC, Maestú F, Vidaurre D. (2015) Guiding functional connectivity estimation by structural connectivity in MEG: an application to discrimination of conditions of mild cognitive impairment. Neuroimage. 101:765-77. PMID: 25111472

Rathbone CJ, Holmes EA, Murphy SE, Ellis JA. (2015) Autobiographical memory and well-being in aging: The central role of semantic self-images. Conscious Cogn. 33:422-31. PMID: 25781408

Sexton CEBetts JFDemnitz NDawes HEbmeier KPJohansen-Berg H. (2015) A systematic review of MRI studies examining the relationship between physical fitness and activity and the white matter of the ageing brain. Neuroimage. In press. PMID: 26477656

Vaikath NN, Majbour NK, Paleologou KE, Ardah MT, van Dam E, van de Berg WD, Forrest SL, Parkkinen L, Gai WP, Hattori N, Takanashi M, Lee SJ, Mann DM, Imai Y, Halliday GM, Li JY, El-Agnaf OM. (2015) Generation and characterization of novel conformation-specific monoclonal antibodies for α-synuclein pathology. Neurobiol Dis. 79:81-99. PMID: 25937088

Weller RO, Hawkes CA, Carare RO, Hardy J. (2015) Does the difference between PART and Alzheimer's disease lie in the age-related changes in cerebral arteries that trigger the accumulation of Aβ and propagation of tau? Acta Neuropathol. 129(5):763-6. PMID: 25814152

2014

Ahmadi S, Wade-Martins R. (2014) Familial Alzheimer's disease coding mutations reduce Presenilin-1 expression in a novel genomic locus reporter model. Neurobiol Aging 35(2) doi: 10.1016/j.neurobiolaging.2013.07.026

Bäumer D, East SZ, Tseu B, Zeman A, Hilton D, Talbot K, Ansorge O. (2014) FTLD-ALS of TDP-43 type and SCA2 in a family with a full ataxin-2 polyglutamine expansion. Acta Neuropathol. 128(4):597-604. PMID: 24718895

Esiri MM, Joachim C, Sloan C, Christie S, Agacinski G, Bridges LR, Wilcock GK, Smith AD (2014) Cerebral subcortical small vessel disease in subjects with pathologically confirmed Alzheimer disease: a clinicopathologic study in the Oxford Project to Investigate Memory and Ageing (OPTIMA). Alzheimer Dis Assoc Disord. 28(1):30-5. PMID 23842286

Hye A, Riddoch-Contreras J, Baird AL, Ashton NJ, Bazenet C, Leung R, Westman E, Simmons A, Dobson R, Sattlecker M, Lupton M, Lunnon K, Keohane A, Ward M, Pike I, Zucht HD, Pepin D, Zheng W, Tunnicliffe A, Richardson J, Gauthier S, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas M, Lovestone S (2014) Plasma proteins predict conversion to dementia from prodromal disease. Alzheimer's & Dementia.   DOI: 10.1016/j.jalz.2014.05.1749

Noel-Storr AH, McCleery JM, Richard E, Ritchie CW, Flicker L, Cullum SJ, Davis D, Quinn TJ, Hyde C, Rutjes AW, Smailagic N, Marcus S, Black S, Blennow K, Brayne C, Fiorivanti M, Johnson JK, Köpke S, Schneider LS, Simmons A, Mattsson N, Zetterberg H, Bossuyt PM, Wilcock G, McShane R. (2014)  Reporting standards for studies of diagnostic test accuracy in dementia: The STARDdem Initiative. Neurology. 83(4):364-73. PMID: 24944261

Pievani M, Filippini N, van den Heuvel MP, Cappa SF, Frisoni GB (2014) Brain connectivity in neurodegenerative diseases--from phenotype to proteinopathy. Nat Rev Neurol. 10(11):620-33. PMID: 25287597

Sexton CE, Walhovd KB, Storsve AB, Tamnes CK, Westlye LT, Johansen-Berg H, Fjell AM. (2014) Accelerated changes in white matter microstructure during aging: a longitudinal diffusion tensor imaging study. J Neurosci. 34(46). PMID: 25392509

Steins D, Sheret I, Dawes H, Esser P, Collett J. (2014) A smart device inertial-sensing method for gait analysis. 47(15):3780-5. PMID: 25305689

Suri S, Mackay CE, Kelly ME, Germuska M, Tunbridge EM, Frisoni GB, Matthews PM, Ebmeier KP, Bulte DP, Filippini N.(2014) Reduced cerebrovascular reactivity in young adults carrying the APOE ε4 allele.Alzheimers Dement. pii: S1552-5260(14)02467-4. PMID: 25160043

Suri S, Topiwala A, Mackay CE, Ebmeier KP, Filippini N. (2014) Using structural and diffusion magnetic resonance imaging to differentiate the dementias Curr Neurol Neurosci Rep. 14(9):475. PMID: 25030502

2013

Barker R, Wellington D, Esiri MM, Love S. (2013) Assessing white matter ischemic damage in dementia patients by measurement of myelin proteins. J Cereb Blood Flow Metab. 33(7):1050-7.

Bullock JM, Medway C, Cortina-Borja M, Turton JC, Prince JA, Ibrahim-Verbaas CA, Schuur M, Breteler MM, van Duijn CM, Kehoe PG, Barber R, Coto E, Alvarez V, Deloukas P, Hammond N, Combarros O, Mateo I, Warden DR, Lehmann MG, Belbin O, Brown K, Wilcock GK, Heun R, Kölsch H, Smith AD, Lehmann DJ, Morgan K. (2013) Discovery by the Epistasis Project of an epistatic interaction between the GSTM3 gene and the HHEX/IDE/KIF11 locus in the risk of Alzheimer's disease. Neurobiol Aging. 34(4):1309.e1-7.

Doherty KM, Silveira-Moriyama L, Parkkinen L, Healy DG, Farrell M, Mencacci NE, Ahmed Z, Brett FM, Hardy J, Quinn N, Counihan TJ, Lynch T, Fox ZV, Revesz T, Lees AJ, Holton JL. (2013) Parkin Disease: A Clinicopathologic Entity? JAMA Neurol. 70(5):571-9.

Douaud G, Refsum H, de Jager CA, Jacoby R, Nichols TE, Smith SM, Smith AD. (2013) Preventing Alzheimer’s disease-related gray matter atrophy by B-vitamin treatment. Proc Natl Acad Sci U S A. 110(23):9523-8.

McAleese KE, Firbank M, Hunter D, Sun L, Hall R, Neal JW, Mann DM, Esiri M, Jellinger KA, O'Brien JT, Attems J. (2013) Magnetic resonance imaging of fixed post mortem brains reliably reflects subcortical vascular pathology of frontal, parietal and occipital white matter. Neuropathol Appl Neurobiol. Aug;39(5):485-97. doi: 10.1111/j.1365-2990.2012.01310.x.

Medway C, Combarros O, Cortina-Borja M, Butler HT, Ibrahim-Verbaas CA, de Bruijn RF, Koudstaal PJ, van Duijn CM, Ikram MA, Mateo I, Sánchez-Juan P, Lehmann MG, Heun R, Kölsch H, Deloukas P, Hammond N, Coto E, Alvarez V, Kehoe PG, Barber R, Wilcock GK, Brown K, Belbin O, Warden DR, Smith AD, Morgan K, Lehmann DJ. (2013) The sex-specific associations of the aromatase gene with Alzheimer’s disease and its interaction with IL10 in the Epistasis Project. Eur J Hum Genet. 22(2) doi: 10.1038/ejhg.2013.116

Thomas M, Alegre-Abarrategui J, Wade-Martins R. (2013) RNA dysfunction and aggrephagy at the centre of an amyotrophic lateral sclerosis/frontotemporal dementia disease continuum. Brain. 136(Pt 5):1345-60.

Zamboni G, Wilcock GK, Douaud G, Drazich E, McCulloch E, Filippini N, Tracey I, Brooks JC, Smith SM, Jenkinson M, Mackay CE. (2013) Resting Functional Connectivity Reveals Residual Functional Activity in Alzheimer’s Disease. Biol Psychiatry. 74(5):375-83 DOI: 10.1016/j.biopsych.2013.04.015

Zamboni G, de Jager CA, Drazich E, Douaud G, Jenkinson M, Smith AD, Tracey I, Wilcock GK. (2013) Structural and functional bases of visuospatial associative memory in older adults. Neurobiol Aging. 34(3):961-72.