Beyond neurotoxicity: A new face of 6-hydroxydopamine in cancer immunity

Sarker G., Domingos A.

In this issue of Neuron , Yu et al. show that 6-hydroxydopamine (6-OHDA) suppresses tumor growth beyond its established sympathetic neurotoxic activity by inducing a macrophage-TH1 immune axis, uncovering an unexpected immunomodulatory role with potential therapeutic implications for breast cancer.

DOI

10.1016/j.neuron.2026.05.028

Type

Journal article

Publication Date

2026-07-15T00:00:00+00:00

Volume

114

Pages

2489 - 2491

Total pages

2

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