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New study shows clinical symptoms for Alzheimer’s can be predicted in preclinical models

OPDC News Publication Research Wade-Martins Group News

Establishing preclinical models of Alzheimer’s that reflect in-life clinical symptoms of each individual is a critically important goal, yet so far it has not been fully realised. A new collaborative study from the University of Oxford has demonstrated that clinical vulnerability to an abnormally abundant protein in Alzheimer’s brain is in fact reflected in individual patient induced pluripotent stem cell-derived cortical neurons.

Joaquim Vieira recognised in national image competition

Awards and Honours Vieira Group News

DPAG BHF Intermediate Research Fellow Dr Joaquim Vieira has been shortlisted for the British Heart Foundation’s annual ‘Reflections of Research’ image competition.

Updating the circuit maps of the sympathetic neural network

Domingos Group News Publication Research

A new review from Professor Ana Domingos’ lab and colleagues offers a fresh modern viewpoint on sympathetic neurons and their relation to immune cells and obesity.

New Pfizer grant paves the way to a better understanding of how body fat is controlled

Awards and Honours Domingos Group News EDI News Research

Professor Ana Domingos has been awarded a highly competitive independent research grant from Pfizer to discover ‘the role of Sympathetic-associated Perineurial barrier Cells in obesity’.

Vladyslav Vyazovskiy reflects on the Braemar Summit 2022

Long Read Vyazovskiy Group News

Professor of Sleep Physiology Vladyslav Vyazovskiy was invited to attend the Braemar Summit 2022, a prestigious annual conference attended by around 100 participants, showcasing the best that is being said and thought in the UK.

Mark Selwood to represent GB at the World Transplant Games

Awards and Honours

Congratulations are in order for DPAG Lab Technician Mark Selwood, who has been chosen to represent Great Britain and Northern Ireland at the 24th World Transplant Games to be held in Australia next year.

Collaborative MRC grant paves the way to new therapeutic targets for stress and anxiety disorders

Awards and Honours Integrative Neuroscience Molnar Group News Research

Dr Armin Lak, Associate Professor Ed Mann and Professor Zoltán Molnár have been awarded a £733K Project Grant from the Medical Research Council on “Orexinergic projections to neocortex: potential role in arousal, stress and anxiety-related disorders”.

How desk jobs alter your brain – and why they’re so tiring

Integrative Neuroscience Molnar Group News Outreach

A fascinating new article on The Conversation website by DPAG's Professor Zoltán Molnár and Professor Tamas Horvath from Yale University.

Richard Tsien delivers Burdon Sanderson Prize Lecture 2022

General Head of Department's News

The annual Burdon Sanderson Prize lecture, given this year by Professor Richard W. Tsien, a pioneer in the study of calcium channels and synaptic transmission, is held in honour of John Burdon Sanderson (1828 - 1905), the University of Oxford's first Waynflete Professor of Physiology, after whom the Cardiac Centre is named.

Denis Noble unveils Blue Plaque to honour Sir John Burdon Sanderson

General Head of Department's News

On Monday 17 October 2022, as part of The Physiological Society roadshow at the University of Oxford, Emeritus Professor of Cardiovasular Physiology Denis Noble FRS unveiled a new plaque honouring the Department's first Waynflete Professor of Physiology, Sir John Burdon Sanderson.

Blue Plaque unveiled to honour Mabel FitzGerald at her long-time Oxford residence

EDI News General Head of Department's News

Attended by Head of Department Professor David Paterson, an Oxfordshire Blue Plaque commemorating Mabel Purefoy FitzGerald (1872 - 1973), pioneering physiologist and high altitude explorer, was unveiled on Friday 14 October at 12 Crick Road, Oxford.

DPAG Myth Busters and Shaping Destiny teams engage the public at IF Oxford 2022

EDI News Outreach Postdoctoral Srinivas Group news Students

Two DPAG-led teams of volunteers engaged hundreds of visitors at Wesley Memorial Church on Saturday 8 October 2022 as part of The Oxford Science and Ideas Festival’s Explorazone. The Myth Busters team assembled by DPAG’s Outreach and Public Engagement Working Group sought to discuss and debunk myths and misconceptions of biology. The Shaping Destiny team run by members of the Srinivas Group, IDRM, in collaboration with Prof Wes Williams at TORCH explored with the public what is human and how body forms have been historically perceived with a unique virtual reality experience.

Peregrine Green wins HRC 2022 Young Investigator Award

Awards and Honours Cardiac Theme Herring Group News Students

Congratulations are in order for Dr Peregrine Green, who has received the Young Investigator award at the Heart Rhythm Congress 2022.

New computational technique reveals changes to lung function post COVID-19 infection

Cell Physiology Publication Research

A collaborative DPAG-led study studied patients at six and twelve months after COVID-19 infection, finding that prior COVID-19 infection was associated with more uneven inflation of the lungs during normal breathing. There was also an association between hospitalisation with COVID-19 and smaller lung volumes, and admission to the intensive care unit (ICU) was associated with an enlarged respiratory dead space.

BHF funded DPAG projects to receive share of £2 million raised by the London Marathon

De Val Group News Outreach Research Vieira Group News

The British Heart Foundation were charity of the year for the 2022 TCS London Marathon. Around 800 BHF London Marathon runners, including former De Val lab researcher Dr Alice Preston, have raised nearly £2 million, and rising, for BHF-funded science that could lead to improved new treatments for heart failure. Research led by Associate Professor Sarah De Val and Dr Joaquim Vieira are two of eight projects to receive funding from these proceeds.

Zoltán Molnár honoured by the Royal Society of Biology

Awards and Honours Integrative Neuroscience Molnar Group News

Congratulations are in order to Professor Zoltán Molnár on being elected Fellow of the Royal Society of Biology.

Vladyslav Vyazovskiy elected Vice President of the European Sleep Research Society

Awards and Honours Vyazovskiy Group News

Congratulations are in order to Professor Vladyslav Vyazovskiy on his appointment as Vice President (Basic) of the European Sleep Research Society (ESRS).

Head of Department congratulates 2022 Nobel Prize winner

Head of Department's News

Professor David Paterson, Head of the Department of Physiology, Anatomy and Genetics and President of The Physiological Society congratulates Professor Svante Pääbo ForMemRS, who has been awarded the 2022 Nobel Prize in Physiology or Medicine.

New evidence for how our brains handle surprise

Bruno Group News Integrative Neuroscience Publication Research

A new study from the Bruno Group is challenging our perceptions of how the different regions of the cerebral cortex function. A group of ‘quiet’ cells in the somatosensory cortex that rarely respond to touch have been found to react mainly to surprising circumstances. The results suggest their function is not necessarily driven by touch, but may indicate an important and previously unidentified role across all the major cortices.

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