{ "items": [ "\n\n
\n \n\n \n \n \n \n Postdoctoral\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n \n \n Srinivas Group news\n \n \n\n \n\n\n
\n \n\n \n18 November 2021
\n \n \n \nScientists have shed light on an important stage of early embryonic development that has never been fully mapped out in humans before.
\n \n\n \n \n\n \n\n \n \n \n \n Cardiac Theme\n \n \n \n \n Heather Group News\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n\n \n\n\n
\n \n\n \n20 October 2021
\n \n \n \nNew research led by Associate Professor Lisa Heather has found that a drug known as molidustat, currently in clinical trials for another condition, could reduce risk of heart failure after heart attacks.
\n \n\n \n \n\n \n\n \n \n \n \n Cell Physiology\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n\n \n\n\n
\n \n\n \n13 September 2021
\n \n \n \nNew research from the Swietach Group in collaboration with NHS Blood and Transplant has demonstrated that the process of storing blood in blood banks can negatively impact the function of red blood cells and consequently may reduce the effectiveness of blood transfusions, a treatment commonly used to combat anaemia.
\n \n\n \n \n\n \n\n \n \n \n \n Cell Physiology\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n\n \n\n\n
\n \n\n \n3 September 2021
\n \n \n \nNew research from the Parekh and Zaccolo groups reveals that a prototypical anchoring protein, known to be responsible for regulating several important physiological processes, also\u00a0orchestrates the formation of two important universal second messengers.
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\n \n\n \n24 August 2021
\n \n \n \nNew article on The Conversation website written by Dr Lukas Krone, Associate Professor Vladyslav Vyazovskiy and Professor Zolt\u00e1n Moln\u00e1r.
\n \n\n \n \n\n \n\n \n \n \n \n Domingos Group News\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n\n \n\n\n
\n \n\n \n20 August 2021
\n \n \n \nA pioneering collaborative mouse study from an international team of researchers including DPAG's Associate Professor Ana Domingos published in Nature offers new therapeutic avenues for reducing visceral fat stores, which have been associated with cardiovascular disease and multiple types of cancer.
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\n \n\n \n5 August 2021
\n \n \n \nMore research is needed to improve the treatment of brain diseases such as depression, Alzheimer\u2019s or ADHD. A widely held view within the scientific community is that this cannot be done without ethically conducted animal research. A team of seventy international neuroscientists, including DPAG\u2019s Associate Professor Vladyslav Vyazovskiy, have now published a warning that animal research is under pressure, which endangers the further development of treatments.
\n \n\n \n \n\n \n\n \n \n \n \n Integrative Neuroscience\n \n \n \n \n Molnar Group News\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n \n \n Vyazovskiy Group News\n \n \n\n \n\n\n
\n \n\n \n2 August 2021
\n \n \n \nWhy we sleep, and the processes behind sleep, are amongst the most interesting questions in modern neuroscience. Researchers at the University of Oxford, including DPAG's Moln\u00e1r and Vyazovskiy group scientists, have now uncovered a new target for sleep investigations within the mammalian brain \u2013 the cerebral cortex. The paper, first authored by Dr Lukas Krone, was published today in Nature Neuroscience.
\n \n\n \n \n\n \n\n \n \n \n \n Heather Group News\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n\n \n\n\n
\n \n\n \n29 July 2021
\n \n \n \nNew research from the Heather Group has shown that in type 2 diabetes an overload of lipids reduces the heart\u2019s ability to generate energy during a heart attack, decreasing chances of recovery.
\n \n\n \n \n\n \n\n \n \n \n \n Integrative Neuroscience\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n\n \n\n\n
\n \n\n \n16 July 2021
\n \n \n \nA new study by the Lak group reveals a novel facet of dopamine signalling during visual decision making.
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\n \n\n \n5 July 2021
\n \n \n \nA team of international collaborators including DPAG's Dr Mootaz Salman has been researching a promising new therapeutic for the treatment of strokes and other brain injuries.
\n \n\n \n \n\n \n\n \n \n \n \n Domingos Group News\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n\n \n\n\n
\n \n\n \n2 July 2021
\n \n \n \nThe Domingos lab has published a new opinion piece in Science investigating the implications of a Memorial Sloan Kettering Cancer Center study that lays the foundations for a potential new anti-obesity treatment in the form of targeting adipose tissue-resident macrophages.
\n \n\n \n \n\n \n\n \n \n \n \n Integrative Neuroscience\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n\n \n\n\n
\n \n\n \n28 June 2021
\n \n \n \nIntegration of information across the senses is critical for perception. This activity is thought to arise primarily from connections made in the brain's sensory cortical areas. A new paper from the King Group uncovers evidence for the first time on the little understood role of subcortical circuits in shaping the multisensory properties of primary cortical neurons.
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\n \n\n \n8 June 2021
\n \n \n \nIn animal models, iron deficient mothers have a greatly increased risk of having offspring with congenital heart disease (CHD). The risk of CHD can be greatly reduced if the mother is given iron supplements very early in pregnancy. Additionally, embryos from a mouse model of Down Syndrome were particularly vulnerable to the effects of maternal iron deficiency, leading to a higher risk of developing severe heart defects.
\n \n\n \n \n\n \n\n \n \n \n \n Cell Physiology\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n\n \n\n\n
\n \n\n \n18 May 2021
\n \n \n \nA new study from the Parekh Group has resolved a long-standing question in our understanding of intracellular Ca2+ signalling, namely how a specific type of Ca2+ channel is uniquely able to signal to the nucleus to regulate gene expression. By unravelling this mechanism, researchers have identified a new approach for developing immunosuppressant drugs.
\n \n\n \n \n\n \n\n \n \n \n \n Lakhal-Littleton Group News\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n\n \n\n\n
\n \n\n \n17 May 2021
\n \n \n \nA new study from the Lakhal-Littleton Group has addressed a long-standing gap in our understanding of systemic iron homeostasis. It provides the first formal demonstration that the hormone hepcidin controls iron reabsorption in the kidney, in a manner that impacts the body\u2019s iron levels, under normal physiological conditions. It also demonstrates for the first time how this mechanism becomes critically important in the development of iron disorders.
\n \n\n \n \n\n \n\n \n \n \n \n Integrative Neuroscience\n \n \n \n \n Molnar Group News\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n\n \n\n\n
\n \n\n \n14 April 2021
\n \n \n \nA new study from the Moln\u00e1r group on the role of regulated synaptic vesicular release in specialised synapse formation has made it to the cover of Cerebral Cortex.
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\n \n\n \n7 April 2021
\n \n \n \nA new study from the Vyazovskiy group suggests that how and where we spend our time while awake impacts how much we need to sleep - it does not only depend on how long we are awake.
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\n \n\n \n30 March 2021
\n \n \n \nA new study from the Smart group has shed light on a key regulatory step in the initiation and progression of Abdominal Aortic Aneurysm by revealing the protective role of a previously little known small protein.
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\n \n\n \n4 March 2021
\n \n \n \nBetina Ip, a Royal Society Dorothy Hodgkin Research Fellow based in NDCN, formerly a postdoctoral research scientist in DPAG, has written a book for children: The Usborne Book of the Brain and How it Works.
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