{ "items": [ "\n\n
\n \n\n \n \n \n \n CNCB\n \n \n \n \n Goodwin Group News\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n\n \n\n\n
\n \n\n \n27 January 2021
\n \n \n \nA new paper from the Goodwin group based in DPAG's Centre for Neural Circuits and Behaviour has shown how males and females are programmed differently in terms of sex.
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\n \n\n \n26 January 2021
\n \n \n \nThe transfer of complex mixtures of signals and nutrients between individuals is a key step in several biologically important events in our lives, such as breastfeeding and sexual intercourse. However, we know relatively little about the ways in which the molecular gifts involved are packaged to ensure their successful delivery to the recipient.
\n \n\n \n \n\n \n\n \n \n \n \n EDI News\n \n \n \n \n Outreach\n \n \n \n \n Postdoctoral\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n\n \n\n\n
\n \n\n \n21 January 2021
\n \n \n \nUniversity of Oxford researchers from the Department of Physiology, Anatomy and Genetics (DPAG) and the Department of Psychiatry, in collaboration with The 1928 Institute, have published a major new study on the impact of COVID-19 on the UK\u2019s largest BME population.
\n \n\n \n \n\n \n\n \n \n \n \n Postdoctoral\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n \n \n Srinivas Group news\n \n \n\n \n\n\n
\n \n\n \n8 January 2021
\n \n \n \nThe earliest known progenitor of the outermost layer of the heart has been characterised for the first time and linked to the development of other critical cell types in the developing heart in a new paper from the Srinivas group led by BHF Immediate Fellow Dr Richard Tyser.
\n \n\n \n \n\n \n\n \n \n \n \n CNCB\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n\n \n\n\n
\n \n\n \n27 November 2020
\n \n \n \nHundreds of dietary supplements have been reported to improve cognitive and emotional function in humans, but few have scientific foundation. A new study from the Waddell group provides fresh insight into how dietary Magnesium supplementation can influence memory performance.
\n \n\n \n \n\n \n\n \n \n \n \n Cardiac Theme\n \n \n \n \n Postdoctoral\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n\n \n\n\n
\n \n\n \n19 November 2020
\n \n \n \nNew research led by Oxford BHF CRE Intermediate Transition Fellow Dr Kerstin Timm shows that a recently developed imaging technique pioneered by the Tyler Group can detect early metabolic changes in the heart caused by a commonly used chemotherapy drug, which is known to increase risk of heart failure in cancer survivors.
\n \n\n \n \n\n \n\n \n \n \n \n Integrative Neuroscience\n \n \n \n \n Postdoctoral\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n \n \n Students\n \n \n\n \n\n\n
\n \n\n \n23 October 2020
\n \n \n \nA computational modelling study from the King Group demonstrates that the way sounds are transformed from the ear to the brain\u2019s auditory cortex may be simpler than expected. These findings not only highlight the value of computational modelling for determining the principles underlying neural processing, but could also be useful for improving treatments for patients with hearing loss.
\n \n\n \n \n\n \n\n \n \n \n \n Cell Physiology\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n \n \n Students\n \n \n\n \n\n\n
\n \n\n \n21 October 2020
\n \n \n \nThe Zaccolo Group has identified a new mechanism that regulates mitochondria quality control, a process that is crucial to maintaining healthy cells and preventing disease.
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\n \n\n \n16 October 2020
\n \n \n \nA new study by Waddell Group Neuroscientists at the Centre for Neural Circuits and Behaviour shows that mobile genetic elements that were active in the genomes of our ancestors could be closely linked to important functions in our brain and might help diversify our behaviour, cognition and emotions.
\n \n\n \n \n\n \n\n \n \n \n \n Integrative Neuroscience\n \n \n \n \n Molnar Group News\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n\n \n\n\n
\n \n\n \n16 October 2020
\n \n \n \nTransient neurones match the spontaneous and sensory driven activities to shape cortical circuits: a landmark collaborative review published in Science from Professor Zolt\u00e1n Moln\u00e1r, Professor Patrick Kanold and Professor Heiko Luhmann.
\n \n\n \n \n\n \n\n \n \n \n \n Cragg Group News\n \n \n \n \n OPDC News\n \n \n \n \n Postdoctoral\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n \n \n Wade-Martins Group News\n \n \n\n \n\n\n
\n \n\n \n2 October 2020
\n \n \n \nA new collaborative study from the Oxford Parkinson\u2019s Disease Centre led by Prof Stephanie Cragg and Dr Bradley Roberts has revealed that GABA transporters on astrocytes, the brain's lesser known yet critically important cells, support dopamine release and are sites of early dysfunction in parkinsonism.
\n \n\n \n \n\n \n\n \n \n \n \n OPDC News\n \n \n \n \n Postdoctoral\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n \n \n Wade-Martins Group News\n \n \n\n \n\n\n
\n \n\n \n28 September 2020
\n \n \n \nA collaborative study led by the OPDC's Dr Nora Bengoa-Vergniory has shown that compounds known as molecular tweezers could become a promising disease modifying therapy for Parkinson\u2019s.
\n \n\n \n \n\n \n\n \n \n \n \n Cardiac Theme\n \n \n \n \n Heather Group News\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n\n \n\n\n
\n \n\n \n4 September 2020
\n \n \n \nA new paper from the Heather and Tyler groups has uncovered the mechanism responsible for reduced energy in the hearts of patients with type 2 diabetes and revealed a new therapeutic strategy to reverse the energy deficit.
\n \n\n \n \n\n \n\n \n \n \n \n Cell Physiology\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n\n \n\n\n
\n \n\n \n1 September 2020
\n \n \n \nCollaborative research from a leading US cancer centre and the Swietach Group has found that Low pH in lymph nodes inhibits effector T cells, while still allowing T cell activation.
\n \n\n \n \n\n \n\n \n \n \n \n OPDC News\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n \n \n Wade-Martins Group News\n \n \n\n \n\n\n
\n \n\n \n25 August 2020
\n \n \n \nNew results from a collaborative Oxford Parkinson\u2019s Disease Centre and Cardiff University study on the cellular origins of Parkinson's could be key to developing new treatments.
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\n \n\n \n13 August 2020
\n \n \n \nTwo new papers from the Vyazovskiy Group and both Oxford University and international collaborators have made important progress in bridging the gap between the local and global levels of sleep regulation.
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\n \n\n \n7 August 2020
\n \n \n \nIn the wake of concern raised about the ethics and risks of performing genetic interventions in macaque monkeys to study models of human neuropsychiatric conditions, Professor Andrew Parker analyses how decision makers evaluate these situations and highlights the ethical consequences if research is not carried out.
\n \n\n \n \n\n \n\n \n \n \n \n Klemm Group News\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n\n \n\n\n
\n \n\n \n7 August 2020
\n \n \n \nAssociate Professor Robin Klemm has edited a special issue for Seminars in Cell and Developmental Biology. \u201cThe molecular cell biology, metabolism and physiological functions of lipid droplets\u201d provides an overview of the most recent developments in the field of lipid droplets, which are important storage organelles at the centre of lipid and energy homeostasis. Prof Klemm joined DPAG in June 2020, bringing with him a new field of research for the department, focusing on the molecular basis of lipid metabolism in professional fat storing cells called adipocytes. His research will impact our basic understanding of the cellular basis of fat metabolism and could lead to innovative new therapies to tackle metabolic disorders such as type II diabetes and obesity.
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\n \n\n \n28 July 2020
\n \n \n \nCollaborative Cancer Research UK-funded studies from DPAG and Oncology researchers have uncovered a new mechanism by which cancer cells adapt to the stresses they encounter as they grow and respond to therapies.
\n \n\n \n \n\n \n\n \n \n \n \n Cell Physiology\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n\n \n\n\n
\n \n\n \n20 July 2020
\n \n \n \nDPAG is among the departments receiving funding from the University's research response fund to undertake COVID-19 research. As part of this effort, the Swietach lab has been studying oxygen transport in the blood of COVID-19 patients. The first results of this study are now published in the British Journal of Haematology and could pave the way for new guidelines for treating the virus.
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