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We experience a wide range of sounds at varying levels. The brain's auditory neurons constantly adapt their responses to changes in sound level to help us perceive and understand what we hear. King Group researchers have previously demonstrated how these neurons do this and have now produced new evidence for exactly where this happens in the brain and the perceptual consequences of these adaptations.
Vladyslav Vyazovskiy will head up new Gordon Research Conference
General Vyazovskiy Group News
17 January 2024
Vladyslav Vyazovskiy will be the first chair of a new Gordon Research Conference on Neurobiology of Psychedelics.
Professor Vladyslav Vyazovskiy penguin paper commentary
General Research Vyazovskiy Group News
1 December 2023
Sian Wilcox awarded Goodger and Schorstein scholarship
Awards and Honours EDI News Students Vyazovskiy Group News
25 May 2023
Congratulations are in order to Sian Wilcox on winning a Goodger and Schorstein Award from the Medical Sciences Internal Fund.
Fellowship to Jose Prius Mengual paves the way to new genetic therapy for epilepsy
Awards and Honours EDI News Postdoctoral Research Vyazovskiy Group News
22 May 2023
Congratulations are in order to Dr Jose Prius Mengual who has been awarded an Emerging Leader Fellowship Award from Epilepsy Research UK and the Nucleic Acid Therapy Accelerator (NATA). With this award, Dr Mengual will develop a new genetic therapy to rebalance protein levels in the neurons affected by epilepsy to prevent seizures.
Can humans hibernate?
Outreach Research Vyazovskiy Group News
20 March 2023
Illuminating new TEDx Talk from Professor of Sleep Physiology Vladyslav Vyazovskiy
New insights into chemogenetic designer drugs to enhance our study of behaviour
Publication Research Vyazovskiy Group News
10 March 2023
A collaborative team of researchers in DPAG and Pharmacology led by Dr Lukas Krone have uncovered striking new data demonstrating that two widely used designer drugs used to turn populations of neurons on and off in the brain cause unexpected effects on sleep. These results demonstrate a critical need to improve chemogenetic approaches in behavioural studies.
New BBSRC grant to further our insights into how the cortex controls sleep
Awards and Honours Integrative Neuroscience Molnar Group News Research Vyazovskiy Group News
15 December 2022
Professor of Sleep Physiology Vladyslav Vyazovskiy and Professor of Developmental Neuroscience Zoltán Molnár have been awarded a Project Grant from the Biotechnology and Biological Sciences Research Council (BBSRC) for “Brain mechanisms of sleep: top-down or bottom-up?”
Raised intracellular chloride levels underlie the effects of tiredness in cortex
Publication Research Vyazovskiy Group News
13 December 2022
A new study, co-authored by Professor Vladyslav Vyazovskiy, published in Nature Neuroscience, has revealed that intracellular chloride levels within cortical pyramidal neurons reflect sleep–wake history.
Vladyslav Vyazovskiy reflects on the Braemar Summit 2022
Long Read Vyazovskiy Group News
1 November 2022
Professor of Sleep Physiology Vladyslav Vyazovskiy was invited to attend the Braemar Summit 2022, a prestigious annual conference attended by around 100 participants, showcasing the best that is being said and thought in the UK.
Vladyslav Vyazovskiy elected Vice President of the European Sleep Research Society
Awards and Honours Vyazovskiy Group News
3 October 2022
Congratulations are in order to Professor Vladyslav Vyazovskiy on his appointment as Vice President (Basic) of the European Sleep Research Society (ESRS).
Little understood brain region linked to how we perceive pain
Integrative Neuroscience Publication Research Vyazovskiy Group News
28 March 2022
A new DPAG-led review paper, published in the journal Brain, has shown that a poorly understood region of the brain called the claustrum may play an important role in how we experience pain.
Switch with a spring: a new model for sleep regulation
Publication Research Vyazovskiy Group News
16 December 2021
New collaborative research led by the Vyazovskiy Group has shed new light on the role of the hypothalamus in the transition between sleep and wake states.
Vladyslav Vyazovskiy becomes Professor Vladyslav Vyazovskiy
Awards and Honours Head of Department's News Vyazovskiy Group News
9 December 2021
Congratulations are in order to Vladyslav Vyazovskiy on his conferral of the title of full Professor. Research in the Vyazovskiy Lab aims to understand the fundamental questions of "what is sleep?" and “why do we sleep?”
Feeling tired? Here’s how the brain’s ‘hourglass’ controls your need for sleep – new research
Publication Research Vyazovskiy Group News
24 August 2021
New article on The Conversation website written by Dr Lukas Krone, Associate Professor Vladyslav Vyazovskiy and Professor Zoltán Molnár.
Gosia Cyranka and Sian Wilcox honoured by The Physiological Society
Awards and Honours EDI News Students Vyazovskiy Group News
6 August 2021
DPAG DPhil students Gosia Cyranka and Sian Wilcox have been awarded prestigious Early Career Researcher Prizes at Physiology 2021, The Physiological Society's Annual Conference celebrating first-class physiology.
Continued ethical animal research needed to advance treatment of brain disease, researchers argue
Publication Research Vyazovskiy Group News
5 August 2021
More research is needed to improve the treatment of brain diseases such as depression, Alzheimer’s or ADHD. A widely held view within the scientific community is that this cannot be done without ethically conducted animal research. A team of seventy international neuroscientists, including DPAG’s Associate Professor Vladyslav Vyazovskiy, have now published a warning that animal research is under pressure, which endangers the further development of treatments.
Cortex may regulate the need for sleep
Integrative Neuroscience Molnar Group News Publication Research Vyazovskiy Group News
2 August 2021
Why we sleep, and the processes behind sleep, are amongst the most interesting questions in modern neuroscience. Researchers at the University of Oxford, including DPAG's Molnár and Vyazovskiy group scientists, have now uncovered a new target for sleep investigations within the mammalian brain – the cerebral cortex. The paper, first authored by Dr Lukas Krone, was published today in Nature Neuroscience.
Being "in the zone": how waking activity controls sleep need
Publication Research Vyazovskiy Group News
7 April 2021
A new study from the Vyazovskiy group suggests that how and where we spend our time while awake impacts how much we need to sleep - it does not only depend on how long we are awake.
Lukas Krone to represent Oxford at the Global Young Scientists Summit
Awards and Honours EDI News Head of Department's News Students Vyazovskiy Group News
3 December 2020
Congratulations are in order for Dr Lukas Krone who is one of just five University of Oxford researchers selected to attend the Global Young Scientists Summit 2021.
Lukas Krone honoured by the World Sleep Society
Awards and Honours EDI News Students Vyazovskiy Group News
16 October 2020
Congratulations are in order for Lukas Krone, who has been presented the 2020 Christian Guilleminault Young Investigator Award by the World Sleep Society.