Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we will assume that you are happy to receive all cookies and you will not see this message again. Click 'Find out more' for information on how to change your cookie settings.

Yu-Ling Ma and her team's paper "Ion Channel Targeted Mechanisms of Anti-arrhythmic Chinese Herbal Medicine Xin Su Ning" has been published in Frontiers in Pharmacology.

Yu-Ling

Xin Su Ning (XSN) is a Chinese patented and certified herbal medicine used to treat premature ventricular contractions. A newly published Ma Group study demonstrates XSN’s clinical antiarrhythmic efficacy of 12 years’ use in China without adverse reactions being officially reported.

"The method used and the standard achieved bear high quality and the clinically relevant research in cellular electrophysiology on a traditional herbal medicine aimed to illuminate its clinical antiarrythmic mechanisms." - Dr Yu-Ling Ma.

XSN is only available in China, so the team's discoveries could pave the path for translating XSN to an international standard antiarrhythmic medicine through common effort.

"Due to the multi-component nature of XSN, further studies will reveal the mechanisms of the multi-targeting action of XSN that would help to advance the latest understanding that cardiac arrhythmic diseases are multifactorial and dynamic.

Further studying the action mechanisms of XSN may also help to explain how the multicomponent action helps to reduce/eliminate the adverse reactions that single chemical antiarrhythmic drugs often possess, which has led to concerns regarding the safety of antiarrhythmic drugs used clinically." - Dr Yu-Ling Ma.

The full paper can be viewed here.

Similar stories

Researchers discover novel form of adaptation in the auditory system

DPAG’s auditory neuroscience researchers have found that the auditory system adapts to the changing acoustics of reverberant environments by temporally shifting the inhibitory tuning of cortical neurons to remove reverberation.

Collaborative team driven by DPAG and Chemistry awarded RSC Horizon Prize

The Molecular Flow Sensor Team, with collaborating members principally from DPAG’s Robbins and Talbot groups and the Department of Chemistry, has been named the winner of the Royal Society of Chemistry’s (RSC) Analytical Division Horizon Prize for the development of a new technology for measuring lung function.

REF 2021 results

Oxford Parkinson’s Disease Centre awarded £3.8 million to reveal the role of calcium in Parkinson’s

A collaborative research team led by the Oxford Parkinson’s Disease Centre (OPDC) has been awarded a £3.8 million Wellcome Trust Collaborative Award to study the function of calcium in dopamine neurons, and how this is plays a role in Parkinson’s. Their research will help explain how and why dopamine neurons are vulnerable in the disease and look at how they may be preserved.

The effect of nuclear pH on cardiac gene expression

Research led by Dr Alzbeta Hulikova and Professor Pawel Swietach has, for the first time, described the potential regulation of nuclear acid-base chemistry in neonatal and adult cardiomyocytes, and explained its relevance in the context of heart physiology and pathology.