{ "items": [ "\n\n
\n \n\n \n \n \n \n Cardiac Theme\n \n \n \n \n Herring Group News\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n\n \n\n\n
\n \n\n \n31 May 2023
\n \n \n \nAn exciting new collaborative study from RDM and DPAG researchers has found that fat metabolism could be the key to tackling heart failure.
\n \n\n \n \n\n \n\n \n \n \n \n Awards and Honours\n \n \n \n \n EDI News\n \n \n \n \n Postdoctoral\n \n \n \n \n Research\n \n \n \n \n Vyazovskiy Group News\n \n \n\n \n\n\n
\n \n\n \n22 May 2023
\n \n \n \nCongratulations are in order to Dr Jose Prius Mengual who has been awarded an Emerging Leader Fellowship Award from Epilepsy Research UK and the Nucleic Acid Therapy Accelerator (NATA). With this award, Dr Mengual will develop a new genetic therapy to rebalance protein levels in the neurons affected by epilepsy to prevent seizures.
\n \n\n \n \n\n \n\n \n \n \n \n Awards and Honours\n \n \n \n \n OPDC News\n \n \n \n \n Postdoctoral\n \n \n \n \n Research\n \n \n \n \n Wade-Martins Group News\n \n \n\n \n\n\n
\n \n\n \n4 May 2023
\n \n \n \nCongratulations are in order to Dr Hugo Fernandes who has been awarded a sought after Alzheimer\u2019s Society Dementia Research Leader Fellowship. With this award, Dr Fernandes will reveal the role of dysfunctional lipid metabolism in dementia using innovative self-designed tools and models to identify new therapeutic targets.
\n \n\n \n \n\n \n\n \n \n \n \n CNCB\n \n \n \n \n Postdoctoral\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n\n \n\n\n
\n \n\n \n26 April 2023
\n \n \n \nNew research published in Nature, led by researchers Dr Zeynep Okray, Dr Pedro Jacob and Professor Scott Waddell at the Centre for Neural Circuits and Behaviour, has discovered a detailed neural circuit mechanism that explains how multisensory learning improves memory performance.
\n \n\n \n \n\n \n\n \n \n \n \n Domingos Group News\n \n \n \n \n EDI News\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n \n \n Students\n \n \n\n \n\n\n
\n \n\n \n13 April 2023
\n \n \n \nProfessor Ana Domingos and DPhil student Conan O\u2019Brien review a new study demonstrating that fasting and re-feeding causes monocytes to re-enter the bone marrow and alter the body's response to infection.
\n \n\n \n \n\n \n\n \n \n \n \n Outreach\n \n \n \n \n Research\n \n \n \n \n Vyazovskiy Group News\n \n \n\n \n\n\n
\n \n\n \n20 March 2023
\n \n \n \nIlluminating new TEDx Talk from Professor of Sleep Physiology Vladyslav Vyazovskiy
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\n \n\n \n13 March 2023
\n \n \n \nCongratulations are in order for Postdoctoral Fellow Dr Annie Park who has been awarded a prestigious Wellcome Early-Career Award.
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\n \n\n \n10 March 2023
\n \n \n \nA collaborative team of researchers in DPAG and Pharmacology led by Dr Lukas Krone have uncovered striking new data demonstrating that two widely used designer drugs used to turn populations of neurons on and off in the brain cause unexpected effects on sleep. These results demonstrate a critical need to improve chemogenetic approaches in behavioural studies.
\n \n\n \n \n\n \n\n \n \n \n \n Cardiac Theme\n \n \n \n \n Postdoctoral\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n\n \n\n\n
\n \n\n \n9 March 2023
\n \n \n \nA new Zaccolo group study has revealed key new insights into the role of cAMP signalling in both healthy and disease settings within the heart. They have identified new cAMP nanodomains in cardiac muscle cells that have far reaching implications for the treatment of heart disease.
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\n \n\n \n8 March 2023
\n \n \n \nCollaborative work from DPAG and Oncology researchers has revealed a potential new pathway to block the production of a specific group of exosomes made in the cell\u2019s recycling system that can promote the growth of cancerous tumours.
\n \n\n \n \n\n \n\n \n \n \n \n Cardiac Theme\n \n \n \n \n Herring Group News\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n\n \n\n\n
\n \n\n \n31 January 2023
\n \n \n \nResearchers from the Herring group have developed a blood test that measures stress hormone levels after heart attacks. The test \u2013 costing just \u00a310 \u2013 could ensure patients receive timely life-saving treatment.
\n \n\n \n \n\n \n\n \n \n \n \n Awards and Honours\n \n \n \n \n OPDC News\n \n \n \n \n Research\n \n \n \n \n Salman Group News\n \n \n \n \n Wade-Martins Group News\n \n \n\n \n\n\n
\n \n\n \n25 January 2023
\n \n \n \nThe Chief Scientist Office of the Government of Scotland has awarded a collaborative grant of \u00a3298,966 to Dr Mootaz Salman to seek new therapeutic avenues to treat stroke.
\n \n\n \n \n\n \n\n \n \n \n \n Awards and Honours\n \n \n \n \n Integrative Neuroscience\n \n \n \n \n Molnar Group News\n \n \n \n \n Research\n \n \n \n \n Vyazovskiy Group News\n \n \n\n \n\n\n
\n \n\n \n15 December 2022
\n \n \n \nProfessor of Sleep Physiology Vladyslav Vyazovskiy and Professor of Developmental Neuroscience Zolt\u00e1n Moln\u00e1r have been awarded a Project Grant from the Biotechnology and Biological Sciences Research Council (BBSRC) for \u201cBrain mechanisms of sleep: top-down or bottom-up?\u201d
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\n \n\n \n13 December 2022
\n \n \n \nA new study, co-authored by Professor Vladyslav Vyazovskiy, published in Nature Neuroscience, has revealed that intracellular chloride levels within cortical pyramidal neurons reflect sleep\u2013wake history.
\n \n\n \n \n\n \n\n \n \n \n \n Ashcroft Group News\n \n \n \n \n Postdoctoral\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n\n \n\n\n
\n \n\n \n14 November 2022
\n \n \n \nResearch led by Dr Elizabeth Haythorne and Professor Frances Ashcroft reveals high blood glucose reprograms the metabolism of pancreatic beta-cells in diabetes. They have discovered that glucose metabolites, rather than glucose itself, are key to the progression of type 2 diabetes. Glucose metabolites damage pancreatic beta-cell function, so they are unable to release enough of the hormone insulin. Reducing the rate at which glucose is metabolised, and these glucose metabolites build up, can prevent the effects of hyperglycaemia.
\n \n\n \n \n\n \n\n \n \n \n \n OPDC News\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n \n \n Wade-Martins Group News\n \n \n\n \n\n\n
\n \n\n \n10 November 2022
\n \n \n \nEstablishing preclinical models of Alzheimer\u2019s that reflect in-life clinical symptoms of each individual is a critically important goal, yet so far it has not been fully realised. A new collaborative study from the University of Oxford has demonstrated that clinical vulnerability to an abnormally abundant protein in Alzheimer\u2019s brain is in fact reflected in individual patient induced pluripotent stem cell-derived cortical neurons.
\n \n\n \n \n\n \n\n \n \n \n \n Domingos Group News\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n\n \n\n\n
\n \n\n \n3 November 2022
\n \n \n \nA new review from Professor Ana Domingos\u2019 lab and colleagues offers a fresh modern viewpoint on sympathetic neurons and their relation to immune cells and obesity.
\n \n\n \n \n\n \n\n \n \n \n \n Awards and Honours\n \n \n \n \n Domingos Group News\n \n \n \n \n EDI News\n \n \n \n \n Research\n \n \n\n \n\n\n
\n \n\n \n1 November 2022
\n \n \n \nProfessor Ana Domingos has been awarded a highly competitive independent research grant from Pfizer to discover \u2018the role of Sympathetic-associated Perineurial barrier Cells in obesity\u2019.
\n \n\n \n \n\n \n\n \n \n \n \n Awards and Honours\n \n \n \n \n Integrative Neuroscience\n \n \n \n \n Molnar Group News\n \n \n \n \n Research\n \n \n\n \n\n\n
\n \n\n \n25 October 2022
\n \n \n \nDr Armin Lak, Associate Professor Ed Mann and Professor Zolt\u00e1n Moln\u00e1r have been awarded a \u00a3733K Project Grant from the Medical Research Council on \u201cOrexinergic projections to neocortex: potential role in arousal, stress and anxiety-related disorders\u201d.
\n \n\n \n \n\n \n\n \n \n \n \n Cell Physiology\n \n \n \n \n Publication\n \n \n \n \n Research\n \n \n\n \n\n\n
\n \n\n \n5 October 2022
\n \n \n \nA collaborative DPAG-led study studied patients at six and twelve months after COVID-19 infection, finding that prior COVID-19 infection was associated with more uneven inflation of the lungs during normal breathing. There was also an association between hospitalisation with COVID-19 and smaller lung volumes, and admission to the intensive care unit (ICU) was associated with an enlarged respiratory dead space.
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