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Filipa Simões set to advance pro-regeneration heart therapies
Awards and Honours Research Riley Group News Simoes Group News
1 February 2022
Congratulations to Dr Filipa Simões who has been awarded a British Heart Foundation (BHF) Intermediate Basic Science Research Fellowship. She will investigate how immune cells called macrophages facilitate long-lasting heart regeneration in the zebrafish and how this could be harnessed for the human heart.
Hidden lung damage found in Long Covid patients with breathlessness
Postdoctoral Research
31 January 2022
A major collaborative study, in which DPAG’s Dr James Grist plays a key role, involving teams in the universities of Oxford, Sheffield, Cardiff and Manchester, has identified abnormalities in the lungs of Long Covid patients who are experiencing breathlessness. Researchers are using a novel xenon gas scanning method to locate damaged areas that cannot be detected by routine scans.
Christoph Treiber awarded ERC Starting Grant to investigate the origins of behavioural diversity
Awards and Honours CNCB EDI News Research
10 January 2022
Congratulations are in order for postdoctoral research scientist Dr Christoph Treiber who has been awarded a Starting Grant from the European Research Council. His funded project will investigate the genetic components that may contribute to diversity of brain function and behaviour.
Switch with a spring: a new model for sleep regulation
Publication Research Vyazovskiy Group News
16 December 2021
New collaborative research led by the Vyazovskiy Group has shed new light on the role of the hypothalamus in the transition between sleep and wake states.
Oxford-led research maps milestone stage of human development for the first time
Postdoctoral Publication Research Srinivas Group news
18 November 2021
Scientists have shed light on an important stage of early embryonic development that has never been fully mapped out in humans before.
Mapping uncharted networks in the progression of Parkinson’s
Cragg Group News OPDC News Research Wade-Martins Group News
26 October 2021
A major new $9 million project funded by the Aligning Science Across Parkinson’s (ASAP) initiative will map the original circuits vulnerable to Parkinson’s on an unprecedented scale. The project is a collaboration between core investigators Stephanie Cragg, Richard Wade-Martins, and Peter Magill at Oxford, Mark Howe at Boston University and Dinos Meletis at the Karolinska Institutet, as well as collaborators Yulong Li at Peking University and Michael Lin at Stanford University.
Mapping uncharted networks in the progression of Parkinson’s
Cragg Group News OPDC News Research Wade-Martins Group News
26 October 2021
A major new $9 million project funded by the Aligning Science Across Parkinson’s (ASAP) initiative will map the original circuits vulnerable to Parkinson’s on an unprecedented scale. The project is a collaboration between core investigators Stephanie Cragg, Richard Wade-Martins, and Peter Magill at Oxford, Mark Howe at Boston University and Dinos Meletis at the Karolinska Institutet, as well as collaborators Yulong Li at Peking University and Michael Lin at Stanford University.
Drug could help diabetic hearts recover after a heart attack
Cardiac Theme Heather Group News Publication Research
20 October 2021
New research led by Associate Professor Lisa Heather has found that a drug known as molidustat, currently in clinical trials for another condition, could reduce risk of heart failure after heart attacks.
Blood bank storage can reduce ability of transfusions to treat anaemia
Cell Physiology Publication Research
13 September 2021
New research from the Swietach Group in collaboration with NHS Blood and Transplant has demonstrated that the process of storing blood in blood banks can negatively impact the function of red blood cells and consequently may reduce the effectiveness of blood transfusions, a treatment commonly used to combat anaemia.
Overlapping second messengers increase dynamic control of physiological responses
Cell Physiology Publication Research
3 September 2021
New research from the Parekh and Zaccolo groups reveals that a prototypical anchoring protein, known to be responsible for regulating several important physiological processes, also orchestrates the formation of two important universal second messengers.
Feeling tired? Here’s how the brain’s ‘hourglass’ controls your need for sleep – new research
Publication Research Vyazovskiy Group News
24 August 2021
New article on The Conversation website written by Dr Lukas Krone, Associate Professor Vladyslav Vyazovskiy and Professor Zoltán Molnár.
Scientists Decipher How NeuroImmune Interactions Burn Deep Fat
Domingos Group News Publication Research
20 August 2021
A pioneering collaborative mouse study from an international team of researchers including DPAG's Associate Professor Ana Domingos published in Nature offers new therapeutic avenues for reducing visceral fat stores, which have been associated with cardiovascular disease and multiple types of cancer.
Study set to detect hidden lung damage in Long Covid Patients
Postdoctoral Research
6 August 2021
Following the successful identification of long-term previously invisible lung damage in post-Covid patients, a large NIHR grant will enable a University of Oxford team including DPAG's Dr James Grist to continue this crucial work to shed light on why people with confirmed Long Covid continue to experience breathlessness following recovery from Covid-19.
Continued ethical animal research needed to advance treatment of brain disease, researchers argue
Publication Research Vyazovskiy Group News
5 August 2021
More research is needed to improve the treatment of brain diseases such as depression, Alzheimer’s or ADHD. A widely held view within the scientific community is that this cannot be done without ethically conducted animal research. A team of seventy international neuroscientists, including DPAG’s Associate Professor Vladyslav Vyazovskiy, have now published a warning that animal research is under pressure, which endangers the further development of treatments.
Cortex may regulate the need for sleep
Integrative Neuroscience Molnar Group News Publication Research Vyazovskiy Group News
2 August 2021
Why we sleep, and the processes behind sleep, are amongst the most interesting questions in modern neuroscience. Researchers at the University of Oxford, including DPAG's Molnár and Vyazovskiy group scientists, have now uncovered a new target for sleep investigations within the mammalian brain – the cerebral cortex. The paper, first authored by Dr Lukas Krone, was published today in Nature Neuroscience.
Reducing fat in the diabetic heart could improve recovery from heart attack
Heather Group News Publication Research
29 July 2021
New research from the Heather Group has shown that in type 2 diabetes an overload of lipids reduces the heart’s ability to generate energy during a heart attack, decreasing chances of recovery.
The brain’s one-sided teaching signals
Integrative Neuroscience Publication Research
16 July 2021
A new study by the Lak group reveals a novel facet of dopamine signalling during visual decision making.
Fellowship awarded to Huriye Atilgan to enhance our understanding of value-based decision-making
Awards and Honours EDI News Integrative Neuroscience Postdoctoral Research
7 July 2021
Congratulations are in order for Postdoctoral Research Scientist Dr Huriye Atilgan who has been awarded a prestigious Sir Henry Wellcome Postdoctoral Fellowship funded by the Wellcome Trust.
The future of stroke treatment
Publication Research Salman Group News Wade-Martins Group News
5 July 2021
A team of international collaborators including DPAG's Dr Mootaz Salman has been researching a promising new therapeutic for the treatment of strokes and other brain injuries.
New review reveals proof of concept for an anti-obesity immunotherapy
Domingos Group News Publication Research
2 July 2021
The Domingos lab has published a new opinion piece in Science investigating the implications of a Memorial Sloan Kettering Cancer Center study that lays the foundations for a potential new anti-obesity treatment in the form of targeting adipose tissue-resident macrophages.