Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

This paper explores the development of multi-feature classification techniques used to identify tremor-related characteristics in the Parkinsonian patient. Local field potentials were recorded from the subthalamic nucleus and the globus pallidus internus of eight Parkinsonian patients through the implanted electrodes of a Deep brain stimulation (DBS) device prior to device internalization. A range of signal processing techniques were evaluated with respect to their tremor detection capability and used as inputs in a multi-feature neural network classifier to identify the activity of Parkinsonian tremor. The results of this study show that a trained multi-feature neural network is able, under certain conditions, to achieve excellent detection accuracy on patients unseen during training. Overall the tremor detection accuracy was mixed, although an accuracy of over 86% was achieved in four out of the eight patients.

Original publication

DOI

10.1016/j.jneumeth.2012.06.027

Type

Journal article

Journal

J Neurosci Methods

Publication Date

15/08/2012

Volume

209

Pages

320 - 330

Keywords

Deep Brain Stimulation, Electrodes, Implanted, Electromyography, Evoked Potentials, Globus Pallidus, Humans, Neural Networks, Computer, Parkinson Disease, Spectrum Analysis, Subthalamic Nucleus, Time Factors, Tremor