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Here we review the mechanisms by which Thymosin beta4 (Tbeta4) regulates angiogenesis, its role in processes, such as wound healing and tumour progression and we discuss in more detail the role of Tbeta4 in the cardiovascular system and significant recent findings implicating Tbeta4 as a potential therapeutic agent for ischaemic heart disease.

Original publication

DOI

10.1007/s10456-007-9077-x

Type

Journal article

Journal

Angiogenesis

Publication Date

2007

Volume

10

Pages

229 - 241

Keywords

Animals, Humans, Neoplasms, Neovascularization, Pathologic, Neovascularization, Physiologic, Thymosin, Wound Healing