About Us
The Oxford Parkinson's Disease Centre (OPDC) is a unique multidisciplinary research program at the University of Oxford. The OPDC was established in February 2010 and brings together internationally-renowned scientists who work on the genetics of Parkinson’s, the generation of cell and animal models, and the wiring of brain circuits which control movement, with clinical experts in the diagnosis and treatment of Parkinson’s.
Our world-class research centre works to understand the earliest events in the development of Parkinson’s with an ultimate view to target the molecular mechanisms of disease with neuroprotective therapies to prevent disease onset or delay progression.
Our program is focused on the molecular pathways to Parkinson’s in order to:
- Predict the onset of Parkinson’s
- Understand the progression of Parkinson’s
- Identify potential drug targets for Parkinson's
- Develop new treatments that will prevent the development of Parkinson’s in at-risk individuals.
Watch the video below to learn more about OPDC's research:
Latest News
Latest publications
Cerebral blood flow as a mechanistic framework across neurological disease
Journal article
Patel S. et al, (2026), Discover Neuroscience, 21
CreER activation transiently disrupts angiogenesis by reducing proliferation and promoting apoptosis in vascular endothelial cells
Journal article
Ioannou E. et al, (2026), Angiogenesis, 29
Minimally invasive versus open transforaminal lumbar interbody fusion for low grade lumbar spondylolisthesis: a systematic review and meta-analysis.
Journal article
Patel S. et al, (2026), Spine Deform
5-HT4 Receptor Ligand RS67333 Modulates Striatal Acetylcholine and Dopamine Release via the Inhibition of Acetylcholinesterase.
Journal article
Qiao Q. et al, (2026), ACS Chem Neurosci
Patient experiences of tissue donation and digital consent support in primary craniospinal tumour research.
Journal article
Mawhinney G. et al, (2026), Support Care Cancer, 34
Deletion of Snap25 disrupts glial remodeling in aging mouse brain.
Journal article
Vadisiute A. et al, (2026), iScience, 29

