Clive Wilson graduated in Biochemistry from the University of Cambridge in 1983 and received his doctorate in 1986 from the University of Warwick. He first worked with fruit flies as a postdoctoral fellow in the labs of Walter Gehring (Basel, 1987-1990) and Hermann Steller (Cambridge, USA, 1990-1993), before returning to the UK as a Lecturer at the University of Kent. Clive moved to Oxford as a Lecturer in Biomedical Sciences in 2001. He is also a Tutorial Fellow in Medicine at St. Hugh's College.

The primary aims of the Wilson lab are to employ the powerful genetics and cell biology of the fruit fly, Drosophila melanogaster, both to generate novel disease models and to elucidate the cellular and biological functions of evolutionarily conserved signalling cascades. Current studies are particularly focused on the development of a novel prostate cancer model in flies and the dissection of signalling by insulin-like molecules and its physiological functions. Insulin signalling is now thought to be of central importance in a number of major human diseases including diabetes, cancer and several neurodegenerative disorders like Alzheimer’s Disease and Parkinson’s Disease, and is also known to modulate the ageing process. Work in our laboratory continues to provide new insights into how insulin signalling plays such diverse roles in disease, and into novel components of the pathway that might be targeted in new clinical strategies to treat insulin-linked disorders.

Further information can be found at Wilson research